Department of Clinical Sciences Malmö Head: Martin Ridderstråle The prevalence of obesity and type 2 diabetes (T2DM) is increasing worldwide. Although our therapeutic arsenal to beget these conditions and their consequences in the form of cardiovascular morbidity and mortality is increasing a lot still needs to be learned about the underlying mechanisms. This project deals with clinical care and t

https://www.ludc.lu.se/research-0/clinical-obesity - 2025-07-03

Leaders of work package 7: Jan Nilsson and Olle Melander This work package focuses on diabetes-driven cardiovascular disease (CVD). The mild age-related diabetes (MARD) cluster, together with the mild obesity-related diabetes (MOD) and the severe insulin-resistant diabetes (SIRD) has the highest risk of developing CVD.Central to the studies in this work package are a number of well-characterised c

https://www.ludc.lu.se/ludc-irc/mild-age-related-diabetes-mard-mechanisms-and-pathways - 2025-07-03

News from the Innovation Office.

https://www.ludc.lu.se/newsletters - 2025-07-03

Leaders of work package 5: Ola Hansson and Eva Degerman SIRD is a novel form of diabetes representing the most insulin resistant (both hepatic and peripheral) form, with most features of the metabolic syndrome but also hepatic steatosis. In this work-package we explore mechanisms and pathways relevant to insulin resistance in various organs and tissues, such as liver, adipose tissue, kidney, skele

https://www.ludc.lu.se/ludc-irc/severe-insulin-resistant-diabetes-sird-mechanisms-and-pathways - 2025-07-03

Leaders of work package 1: Emma Ahlqvist and Dmytro Kryvokhyzha One of the main resources to the LUDC-IRC is the access to large well-phenotyped cohorts, which can be linked to information from the public health care system. Central to the LUDC-IRC work is the exploitation of the more refined diabetes classification, which will help us more systematically search for pathogenic mechanisms underlyin

https://www.ludc.lu.se/ludc-irc/data-harmonisation-and-integration - 2025-07-03

Leaders of work package 8: Gustav Smith and Andreas Edsfeldt LUDC-IRC takes advantage of the accumulated expertise of investigators and resources available to conduct recall trials based on pathogenetically relevant biomarkers or genotypes or based upon subtype of diabetes.Work package 8 has access to  unique, large-scale clinical cohorts that include patients with diabetes and diabetes-associated

https://www.ludc.lu.se/ludc-irc/clinical-validation-randomised-trials-and-interventions - 2025-07-03

Head: Ola Hansson Our research interest is to understand how genetic variation influences skeletal muscle function and whole-body metabolism. We use translational approaches and regularly conduct focused intervention studies in humans, including skeletal muscle biopsies. From the biopsies, muscle stem cells (satellite cells) are isolated and later used for preclinical measurements. In our projects

https://www.ludc.lu.se/research/ola-hansson - 2025-07-03

Albert Salehi’s group The etiology of metabolic syndrome and type 2 diabetes is complex and involves the interaction between both genetic and environmental factors including nutritional state with consequent metabolic signals. There are currently no clinical treatments to prevent, reverse, or efficiently cure the progression of rapid beta-cell demise or insulin resistance in diabetes-prone individ

https://www.ludc.lu.se/research/islet-cell-physiology - 2025-07-03

Head: Karin Stenkula My research group is focused on experimental cell biology research within the diabetes and obesity field. The overall purpose of our research is to explore both normal adipose cell function and the cellular mechanisms causing impaired glucose- and lipid metabolism associated with insulin resistance and type 2 diabetes. At a single cell level, we have shown that the GLUT4 trans

https://www.ludc.lu.se/glucose-transport-and-protein-trafficking - 2025-07-03

Daniel Agardh’s group Our researchThe overall purpose of our research is to uncover the genetic and environmental etiology of three autoimmune diseases – celiac disease, type 1 diabetes, and autoimmune thyroiditis. Specific autoantibody markers are used to predict the clinical onset of these three lifelong autoimmune diseases. Longitudinal studies of children at increased risk allow studies of the

https://www.ludc.lu.se/research/celiac-disease-and-diabetes-unit - 2025-07-03

Head: Karin Berger   According to WHO, improving nutrition is the single most important contributor to reduce the burden of diabetes in Europe. Polyphenols are compounds with anti-oxidative effect providing taste and color in plant-based food. In the last decade, polyphenol-rich foods have received increased interest from researchers and food industry. The main reason for this interest is the reco

https://www.ludc.lu.se/research-0/molecular-nutrition-group - 2025-07-03

Leaders for work package 6: Nils Wierup, Cecilia Holm, and Olga Göransson The mild obesity-related diabetes (MOD) cluster includes the most obese but not the most insulin resistant individuals. Obesity is a common risk factor for type 2 diabetes and its complications. This work package explores the differences between metabolically healthy and unhealthy obesity and focuses on elucidating the mecha

https://www.ludc.lu.se/ludc-irc/mild-obesity-related-diabetes-mod-mechanisms-and-pathways - 2025-07-03

Centre for Evidence-based Psychosocial Interventions, CEPI Centre for Evidence-based Psychosocial Interventions, CEPI, Our research is interdisciplinary and focuses on subjects such as living conditions, support and care initiatives as well as policy and implementation. Through our research, we want to contribute to effective health care and support for persons who experience mental health problem

https://www.cepi.lu.se/cepi-english - 2025-07-03

Ups & Downs in Mental Health mWorks I dialog för psykisk hälsa IPS för personer med beroende Främjande av psykisk hälsa i Generation Z

https://www.cepi.lu.se/forskning-0/forskningsprojekt - 2025-07-03

Ett digitalt hjälpmedel för arbetsåtergång, delaktighet och egenmakt för personer med psykisk ohälsa Bryter den negativa spiralenPsykisk ohälsa är den vanligaste orsaken till sjukskrivning och fokus hamnar lätt på vad man inte kan och vad som inte fungerar på jobbet. Då är det viktigt att få nytt hopp och tro på att man kan jobba. mWorks har utvecklats för att bryta den negativa spiralen vid sjuks

https://www.cepi.lu.se/forskning-0/forskningsprojekt/mworks - 2025-07-03

CEPI har tilldelats medel (Forte, 23,9 miljoner) för att i ett forskningsprogram 2022-2027 utveckla och implementera brukarinflytande. Utlysningen omfattade klient- och praktiknära forskning inom framförallt socialtjänstens verksamhetsområden och går under namnet Tillämpad välfärdsforskning. Forskare och medlemmar i UserInvolve. CEPI är ett tvärprofessionellt centrum där ämnet socialt arbete utgör

https://www.cepi.lu.se/forskning-0/userinvolve-vart-forskningsprogram - 2025-07-03

BakgrundVi söker just nu deltagare till en intervjustudie studie för att ta reda på hur det är att söka och få vård för sin psykiska ohälsa inom primärvården. Med primärvården menar vi elevhälsa, vårdcentral och kommunal hemsjukvård. Vi vill med din hjälp att vården ska bli ännu bättre på psykisk hälsa. Är du över 16 år och vill dela med dig av dina erfarenheter? Då är du välkommen att anmäla ditt

https://www.cepi.lu.se/forskning-0/forskningsprojekt/i-dialog-psykisk-halsa - 2025-07-03

Ett kärt urval av våra CEPIster som träffades i november 2022.  Elisabeth Argentzell, Hälsovetenskaper, Lunds universitetMahmoud Azzam, Kliniska vetenskaper, Lunds universitet, Region SkåneUlrika Bejerholm, Hälsovetenskaper, Lunds universitet, FOUU Region SkåneMaria Bendtsen Kronkvist, Psykiatri, Umeå universitetMagnus Bergmark, Socialt arbete, Umeå universitetSiv-Therese Bogevik Björkedal, Huvuds

https://www.cepi.lu.se/om-cepi/medlemmar - 2025-07-03

En randomiserad kontrollerad studie i en svensk kontext I nuläget saknas en arbetsrehabiliteringsmodell som bevisat ökar möjligheten för personer med beroendeproblematik att nå, få och behålla arbete. Detta vill vi förändra genom vår IPSADAS-studie! Om IPSADASIPSADAS (Individual Placement and Support for persons with alcohol and drug addiction in a Swedish context) är en randomiserad kontrollerad

https://www.cepi.lu.se/forskning-0/forskningsprojekt/ips-personer-med-beroende-av-alkohol-och-droger - 2025-07-03

Med denna forskning vill vi tillsammans med unga vuxna och andra viktiga aktörer, utveckla och utvärdera en e-hälsolösning för att öka unga vuxnas kunskap om psykisk hälsa, hur de kan hjälpa varandra och hitta balans i vardagen. Hög förekomst av psykisk ohälsa bland unga vuxnaEn av de mest akuta utmaningarna i dagens samhälle är den höga förekomsten av psykisk ohälsa bland unga vuxna (18-29 år), ä

https://www.cepi.lu.se/generation-z - 2025-07-03